Lonidamine, mitochondrial hexokinase inhibitor
Biochem/physiol Actions
Inhibits the energy metabolism of neoplastic cells by interfering with hexokinase and disrupting uncoupler-stimulated mitochondrial electron transport; damages cell and mitochondrial membranes.
Packaging
5, 25 mg in glass bottle
| Quality Level | 200 |
|---|---|
| InChI key | WDRYRZXSPDWGEB-UHFFFAOYSA-N |
| InChI | 1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | chloroform: methanol (1:1): 9.80-10.20 mg/mL, clear, colorless to light yellow |
| Form | powder |
| Assay | ≥98% (TLC) |
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