Iodoacetic acid, >=98.0% (T)

Iodoacetic acid, >=98.0% (T)

Stock Code: 3577809
Manufacturer Part No: I4386-100G
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£222.00 (exc VAT) per 100G
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Application


Reagent for the modification of cysteine residues in proteins.


Iodoacetic acid has been used as an alkylating agent for antibody AR37, serum proteins and strawberry proteome samples extracted from different stages of ripened fruit.


Biochem/physiol Actions


Iodoacetic acid (IAA) blocks the thiol group of cysteine. IAA inhibits glyceraldehyde-3-phosphate dehydrogenase (G3PDH) by interacting with sulfhydryl group of the active site cysteine. IAA inhibits the progression of solid Ehrlich carcinoma. IAA is one of the iodinated disinfection byproducts in drinking water. It is cytotoxic to mammalian cells.


Packaging


10, 25, 100 g in glass bottle

Colourwhite to yellow
Quality Level200
mp77-79 °C (lit.)
InChI keyJDNTWHVOXJZDSN-UHFFFAOYSA-N
InChI1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
ManufacturerSIGMA-ALDRICH
Formpowder or flakes
Assay≥98.0% (T)

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