Ethylenediaminetetraacetic acid disodium salt dihydrate, meets analytical specification of Ph. Eur.,

Ethylenediaminetetraacetic acid disodium salt dihydrate, meets analytical specification of Ph. Eur.,

Stock Code: 3577569
Manufacturer Part No: 27285-500G-R
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Application


Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic acid disodium salt dihydrate has been used along with Na2HPO4 and citric acid for preparing Na2EDTA-McIlvaine buffer. Aqueous solution of Ethylenediaminetetraacetic acid disodium salt dihydrate has also been used for photocatalytic hydrogen production


Biochem/physiol Actions


Ethylenediaminetetraacetic acid disodium salt dihydrate is a widely used chelator of divalent cations like Ca+2 and inhibits metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA also acts as a chelator of the zinc ion in the active site of metalloproteases; thus it inhibits metalloproteases that requires zinc for activity. Additionally, EDTA prevents platelet aggregation and is a preferred anticoagulant for platelet counts.

Quality Level200
mp248 °C (dec.) (lit.)
pH4-5 (20 °C, 5%)
InChI keyOVBJJZOQPCKUOR-UHFFFAOYSA-L
InChI1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
ManufacturerSIGMA-ALDRICH
Impurities≤0.001% heavy metals (as Pb); ≤0.001% cyanide (CN); ≤0.1% nitrilotriacetic acid (HPLC) (HPLC); residual solvents, complies
Solubilitywater: soluble 100 g/L at 20 °C
Assay99.0-101.0%
Loss8.7-11.4% loss on drying, 200 °C, 3 h

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