Ethylenediaminetetraacetic acid disodium salt dihydrate, ACS reagent, 99.0-101.0%

Ethylenediaminetetraacetic acid disodium salt dihydrate, ACS reagent, 99.0-101.0%

Stock Code: 3577743
Manufacturer Part No: E4884-100G
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£36.38 (exc VAT) per 100G
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Application


Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic acid disodium salt dehydrate has been used as a component:of radioimmunoprecipitation assay buffer (RIPA buffer) for preparation of C2C12 mouse skeletal myoblastswhole cell lysateof lysis buffer and IgG resin wash and equilibration buffer for the purification of human proteasome regulatory particles (RPs)of M-buffer for the isolation of human cardiomyocyte progenitor cells (CMPCs) from fetal heart


Biochem/physiol Actions


Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline serves as a root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium disodium EDTA administration is effective in slowing down the progression of chronic kidney disease. It also enhances the antimicrobial functionality of lysozyme and improves shelf life of cheese.


General description


EDTA is a chelator of divalent cations. It inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Packaging


100, 500 g in poly bottle

mp248 °C (dec.) (lit.)
InChI keyOVBJJZOQPCKUOR-UHFFFAOYSA-L
InChI1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
ManufacturerSIGMA-ALDRICH
Impurities≤0.1% Nitrilotriacetic acid ([HOCOCH2]3N), ≤0.005% Insoluble matter
Formsolid
Assay99.0-101.0%

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