Benzamidine hydrochloride hydrate, >=99%

Benzamidine hydrochloride hydrate, >=99%

Stock Code: 3577658
Manufacturer Part No: B6506-100G
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£302.61 (exc VAT) per 100G
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Application


Benzamidine hydrochloride hydrate has been used:in western blot analysisin immunoprecipitationin the purification of yeast dyneinas a protease inhibitor in the preparation of brush-border membrane vesiclesfor the processing of human synovial fluid, blood and eye sleepto prevent non-specific degradation of cartilages


Biochem/physiol Actions


Peptidase inhibitor.


Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.


Packaging


5, 25, 100 g in glass bottle


Preparation Note


Benzamidine HCl is soluble in water and alcohol. Solubility testing in water at a concentration of 50 mg/ml yields a clear solution with heating. Benzamidine HCl is sensitive to oxidation. It is recommended to prepare solutions fresh each time in degassed water prior to use. However, frozen aliquots stored under inert gas, to exclude air, may be stable for a short time. Insufficient information is available to assess the shelf-life of a frozen solution.

Quality Level200
mp86-88 °C (lit.)
InChI keyBQVJCMMLDJPBFZ-UHFFFAOYSA-N
InChI1S/C7H8N2.ClH.H2O/c8-7(9)6-4-2-1-3-5-6;;/h1-5H,(H3,8,9);1H;1H2
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥99%

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