3-Isobutyl-1-methylxanthine, BioUltra, >=99%

Stock Code: 3577823
Manufacturer Part No: I7018-250MG

Order Now for 21 day delivery

Descriptions

Application

3-Isobutyl-1-methylxanthine, an inhibitor of adenosine 3?,5?-cyclic monophosphate phosphodiesterase (cAMP PDE), has been used:for adipogenic differentiationin tissue culture3T3-L1 preadipocyte differentiation(

Biochem/physiol Actions

The increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA, leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC₅₀: 1.3 µM). IBMX also serves as an adenosine receptor antagonist. IBMX has been shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. IBMX induces calcium release from intracellular stores in sensory neurons.

Features and Benefits

Trace element testing by ICP ICP testing for trace sulfur (as sulfate) and phosphorus (as phosphate) content Ion chromatography testing for trace ammonium content

Packaging

1 g in poly bottle

Specifications

InChI key	APIXJSLKIYYUKG-UHFFFAOYSA-N
InChI	1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12)
Manufacturer	SIGMA-ALDRICH
Impurities	﹤0.005% Phosphorus (P)
Assay	≥99%