2(3)-O-(4-Benzoylbenzoyl)adenosine 5-triphosphate triethylammonium salt, >=93%
Application
2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate triethylammonium salt has been used as a P2X4 receptor agonist in rat kidney sections, type I diabetes induced rats and astrocyte?neuron coculture. It has also been used as a synthetic ATP analog in isotonic E3 medium.
Useful as a photoaffinity label for proteins and enzymes that bind ATP.
Biochem/physiol Actions
2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate triethylammonium salt is a selective purinergic receptor (P2X) agonist. It is more potent than ATP at homodimeric P2X7 receptors. It also effectively activates P2X1, P2X2, and P2X3 receptors. Useful as a photoaffinity label for proteins and enzymes that bind ATP.
Selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.
General description
2?(3?)-O-(4-Benzoylbenzoyl)adenosine 5?-triphosphate is a photoreactive analog of ATP.
Other Notes
Mixed isomers
Packaging
5, 25 mg in glass bottle
| Quality Level | 200 |
|---|---|
| InChI key | HVOVBTNCGADRTH-WBLDMZOZSA-N |
| InChI | 1S/C24H24N5O15P3.C6H15N/c25-21-17-22(27-11-26-21)29(12-28-17)23-19(31)20(16(41-23)10-40-46(36,37)44-47(38,39)43-45(33,34)35)42-24(32)15-8-6-14(7-9-15)18(30)13- |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | water: 50 mg/mL, clear, colorless to faintly yellow |
| Form | powder |
| Assay | ≥93% |
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