2,3-Dideoxycytidine 5-triphosphate sodium salt, >=90% (HPLC)
Application
Complexes of ddCTP with DNA polymerase β were studied by x-ray crystallography, with implications for inhibitory activity against HIV reverse transcriptase.
Biochem/physiol Actions
Inhibitor of DNA polymerase I-catalyzed chain elongation.
Packaging
1, 2 mg in glass bottle
| Quality Level | 200 |
|---|---|
| InChI key | LOOMQRBEBYCFPP-QDOHZIMISA-M |
| InChI | 1S/C9H16N3O12P3.Na/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16;/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | water: 1 mg/mL, clear, colorless |
| Form | powder |
| Assay | ≥90% (HPLC) |
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