1,10-Phenanthroline monohydrate, reagent grade
Application
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate has been used:as an inhibitor of metalloproteinase (MMP) in MDA-MB-231 breast cancer cellsas a negative control in in situ zymography of mice heart samplesin in vitro resveratrol chelation and reducing activities assays to chelate iron
Biochem/physiol Actions
Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.
General description
Phenanthroline is a heterocyclic organic compound, which forms complexes with metal ions. These complexes have wide applications in biochemistry, catalysis and analytical chemistry. It complexes with iron and is exploited as a redox indicator.
Packaging
1, 5, 25, 100 g in poly bottle
| Quality Level | 200 |
|---|---|
| mp | 100-104 °C (lit.) |
| InChI key | PPQJCISYYXZCAE-UHFFFAOYSA-N |
| InChI | 1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2 |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
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