1,10-Phenanthroline monohydrate, reagent grade

1,10-Phenanthroline monohydrate, reagent grade

Stock Code: 3577893
Manufacturer Part No: P9375-100G
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£1,010.89 (exc VAT) per 100G
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Application


When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.


1,10-Phenanthroline monohydrate has been used:as an inhibitor of metalloproteinase (MMP) in MDA-MB-231 breast cancer cellsas a negative control in in situ zymography of mice heart samplesin in vitro resveratrol chelation and reducing activities assays to chelate iron


Biochem/physiol Actions


Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.


General description


Phenanthroline is a heterocyclic organic compound, which forms complexes with metal ions. These complexes have wide applications in biochemistry, catalysis and analytical chemistry. It complexes with iron and is exploited as a redox indicator.


Packaging


1, 5, 25, 100 g in poly bottle

Quality Level200
mp100-104 °C (lit.)
InChI keyPPQJCISYYXZCAE-UHFFFAOYSA-N
InChI1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2
ManufacturerSIGMA-ALDRICH
Formpowder

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