Vitamin B12, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for p

Stock Code: 3572761
Manufacturer Part No: V6629-1G
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£277.50 (exc VAT) per 1G
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Application


Vitamin B12 has been used:as a component of Erdschreiber?s mediumas a supplement of Dulbecco?s modified Eagle?s medium used for the isolation of ventricular myocytes from neonatal and adult ratsorally administered to male quails to study its role in reducing the negative effects of sodium selenite intoxication, in vivo


Biochem/physiol Actions


Vitamin B12 is metabolized to its active form, methylcobalamin. Hindered vitamin B12 uptake is observed in pernicious anemia. Vitamin B12 is essential for erythroblast development. Pregnancy reduces the levels of vitamin B12. Aging reduces vitamin B12 absorption. It works as a coenzyme in fat, carbohydrate and protein metabolism. It is required for growth, genetic stability and survival of cells in vitro. Functions to support one-carbon metabolism. Present in many classical and serum-free formulations.


General description


Cyanocobalamin (B12) is a water soluble vitamin, commonly called as cobalamins. Dairy products, meat and eggs are the major sources of this vitamin.


Packaging


100, 250 mg in glass bottle


1, 5 g in glass bottle

Colourred to brown
Pack1G
pH6
InChI keyRMRCNWBMXRMIRW-QJRSUKKJSA-L
InChI1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98%

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