Acetylcholine chloride, suitable for cell culture

Acetylcholine chloride, suitable for cell culture

Application

Acetylcholine chloride has been used in the preparation of acetylcholine, that is used as a common vehicle for iontophoresis of acetylcholine (ACh). It has also been used to treat aNS-1 derived neurons for cAMP (cyclic adenosine monophosphate) assay and also used to check their ability to influence G protein-coupled receptors (GPCRs).

Biochem/physiol Actions

Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

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Code Description Quality Level Pack mp InChI key InChI Manufacturer Form Assay Price Quantity
3571295 Acetylcholine chloride, suitable for cell culture 400 100G 146-150 °C (lit.) JUGOREOARAHOCO-UHFFFAOYSA-M 1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1 SIGMA-ALDRICH powder ~99%
£208.75 (exc VAT) per 100G
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3571296 Acetylcholine chloride, suitable for cell culture 400 25G 146-150 °C (lit.) JUGOREOARAHOCO-UHFFFAOYSA-M 1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1 SIGMA-ALDRICH powder ~99%
£60.75 (exc VAT) per 25G
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