Putrescine dihydrochloride, powder, BioReagent, suitable for cell culture

Putrescine dihydrochloride, powder, BioReagent, suitable for cell culture

Stock Code: 3572170
Manufacturer Part No: P5780-25G
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£202.50 (exc VAT) per 25G
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Application


Putrescine dihydrochloride has been used as medium component in F-12 + GlutaMax medium for mice ganglia culture, retinal ganglion cell culture and in HCT116 colon carcinoma cells for ornithine decarboxylase (ODC) assay.


Biochem/physiol Actions


Putrescine is regarded as a marker of stress in plants. External supplementation of putrescine helps wheat plants to overcome drought stress. It is crucial for cell proliferation in animals and modulates abscisic acid (ABA) levels during cold stress in Arabidopsis plants. It serves as an attractant for predators.


Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.


General description


Putrescine is an end product of fatty acid metabolism in dead tissues. It is a volatile diamine with pungent odour. It is synthesized by the decarboxylation of ornithine in the presence of enzyme, ornithine decarboxylase. Molecular docking studies reveal the binding of putrescine to human receptors called the trace amine-associated receptors (TAAR6 and TAAR8), present in olfactory epithelium.

Quality Level200
Pack25G
mp280 °C (dec.) (lit.)
InChI keyXXWCODXIQWIHQN-UHFFFAOYSA-N
InChI1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H
ManufacturerSIGMA-ALDRICH
Product LineBioReagent
Formpowder
Assay≥97% (TLC)

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