N-Butyldeoxynojirimycin, film (dried in situ)

Stock Code: 3586656
Manufacturer Part No: B8299-5MG

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Descriptions

Application

N-Butyldeoxynojirimycin has been used:in the inhibition of glycolipid synthesis in neuroblastoma cellsin the inhibition the ceramide-specific glycosyltransferase in hepatocytesin the inhibition of ?-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.

Biochem/physiol Actions

N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and ?-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.

α-glucosidase Inhibitor

General description

N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.

Packaging

1, 5 mg in glass bottle

Specifications

Quality Level	200
InChI key	UQRORFVVSGFNRO-UTINFBMNSA-N
InChI	1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
Manufacturer	SIGMA-ALDRICH
Solubility	water: 9.80-10.20 mg/mL, clear, colorless
Form	film (dried in situ)
Assay	≥98% (TLC)