Lectin from Phytolacca americana (pokeweed), lyophilized powder

Lectin from Phytolacca americana (pokeweed), lyophilized powder

Analysis Note

Mitogenic activity was determined by BrdU incorporation in HeLa cell cultures.

Application

Lectin from Phytolacca americana (pokeweed) has been used:as a medium supplement for mononuclear cell incubation, to induce lymphocyte proliferation as a positive control in the study of the role of chemokine (C–C motif) ligand 2 (CCL2) in proliferation and apoptosis of decidual leukocytesas a supplement in the RPMI (Roswell park memorial institute) 1640 medium for peripheral blood lymphocyte cultures

Biochem/physiol Actions

Lectin is known to be useful in glycoconjugate characterizing, imaging and targeting. Its use in microarray assay, enable efficient glycome profiling. This is because of its specific interaction with oligosaccharides, glycoproteins and glycolipids. In plants and fungi, lectin defends against pathogens/feeders. Lectin participates in host recognition and tissue adhesion, thereby aids in the pathogenesis of microorganism.

PWM is extracted from pokeweed roots. This protein has hemagglutinating, leukoagglutinating, and mitogenic properties. PWM is not blood group specific, but has affinity for N-acetyl-β-D-glucosamine oligomers.

General description

Lectins are carbohydrate-binding proteins, omnipresent, found in fungi, plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in ?-strands and possesses a carbohydrate binding sites on the surface.

Physical form

Partially purified TCA precipitate.Essentially salt-free.

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Quality Level Manufacturer Storage Temp. Form Price Quantity
3587121 Lectin from Phytolacca americana (pokeweed), lyophilized powder 200 SIGMA-ALDRICH 2-8°C lyophilized powder
£303.64 (exc VAT) per 10MG
-
+
3587122 Lectin from Phytolacca americana (pokeweed), lyophilized powder 200 SIGMA-ALDRICH 2-8°C lyophilized powder
£792.54 (exc VAT) per 40MG
-
+
3587123 Lectin from Phytolacca americana (pokeweed), lyophilized powder 200 SIGMA-ALDRICH 2-8°C lyophilized powder
£162.96 (exc VAT) per 5MG
-
+