3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester, >=95%, powder

Descriptions

Application

3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.It has been used for antibody conjugation and as a protein cross-linker.

General description

3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. It incorporates four atom linker.

Packaging

5 mg in glass bottle

25, 100 mg in poly bottle

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	mp	InChI key	InChI	Manufacturer	Form	Assay	Price	Quantity
3587273	3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester, >=95%, powder	200	84-86 °C (lit.)	JWDFQMWEFLOOED-UHFFFAOYSA-N	1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2	SIGMA-ALDRICH	powder	≥95%	£756.32 (exc VAT) per 100MG	- +
3587274	3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester, >=95%, powder	200	84-86 °C (lit.)	JWDFQMWEFLOOED-UHFFFAOYSA-N	1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2	SIGMA-ALDRICH	powder	≥95%	£252.11 (exc VAT) per 25MG	- +
3587275	3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester, >=95%, powder	200	84-86 °C (lit.)	JWDFQMWEFLOOED-UHFFFAOYSA-N	1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2	SIGMA-ALDRICH	powder	≥95%	£84.41 (exc VAT) per 5MG	- +