Insulin from bovine pancreas, Hybri-Max, powder, suitable for hybridoma

Insulin from bovine pancreas, Hybri-Max, powder, suitable for hybridoma

Stock Code: 3571888
Manufacturer Part No: I4011-100MG
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£711.25 (exc VAT) per 100MG
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Application


Insulin from bovine pancreas has been used in endometrium cell culture. It has also been used to perform insulin tolerance test and to study the effect of protein undernutrition in laying hens.


Insulin from bovine pancreas was used during experimental design and treatments. Experimental animals (like cow) were infused with bovine insulin to decrease blood glucose to a constant level.


Biochem/physiol Actions


Abnormal insulin secretion or function leads to diabetes mellitus, obesity and other carbohydrate metabolism disorders. The biological effects of insulin are mediated by insulin receptor (glycoprotein) and it integrates major signaling pathways.


Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.


General description


The insulin gene is mapped to human chromosome 11p15.5.


Legal Information


Hybri-Max is a trademark of Sigma-Aldrich Co. LLC


Other Notes


InChI:

Quality Level200
Pack100MG
InChI keyIXIBAKNTJSCKJM-BUBXBXGNSA-N
ManufacturerSIGMA-ALDRICH
Impuritiesendotoxin, tested
Formpowder

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