Choline chloride, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, >
Application
Choline chloride has been used:as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cellsfor choline standard curve generation for quantifying phospholipase D (PLD) activityas a component of slice solution for the dissection of entorhinal-hippocampal brain slices
Biochem/physiol Actions
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .
General description
Choline chloride is a quaternary ammonium salt and associates with hydrogen bond donors (HBD). It is essential for the vital physiological functions and is used as a nutritional additive. Choline is a source of methyl groups for methyl-transfer reactions.
Packaging
1 kg in poly drum
100, 500 g in poly bottle
Substrates
Choline acetyltransferase substrate
| Colour | white |
|---|---|
| Pack | 500G |
| mp | 302-305 °C (dec.) (lit.) |
| InChI key | SGMZJAMFUVOLNK-UHFFFAOYSA-M |
| InChI | 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1 |
| Manufacturer | SIGMA-ALDRICH |
| Form | crystals |
| Assay | ≥98% |
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