Choline chloride, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, >

Choline chloride, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, >

Stock Code: 3571478
Manufacturer Part No: C7527-100G
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Application


Choline chloride has been used:as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cellsfor choline standard curve generation for quantifying phospholipase D (PLD) activityas a component of slice solution for the dissection of entorhinal-hippocampal brain slices


Biochem/physiol Actions


The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .


General description


Choline chloride is a quaternary ammonium salt and associates with hydrogen bond donors (HBD). It is essential for the vital physiological functions and is used as a nutritional additive. Choline is a source of methyl groups for methyl-transfer reactions.


Packaging


1 kg in poly drum


100, 500 g in poly bottle


Substrates


Choline acetyltransferase substrate

Colourwhite
Pack100G
mp302-305 °C (dec.) (lit.)
InChI keySGMZJAMFUVOLNK-UHFFFAOYSA-M
InChI1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
ManufacturerSIGMA-ALDRICH
Formcrystals
Assay≥98%

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