alpha-Cyclodextrin, powder, BioReagent, suitable for cell culture, >=98%
Application
Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. ?-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.
Biochem/physiol Actions
?-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, ?-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, ?-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.
General description
?-Cyclodextrin (?-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by ?-(1,4) bonds. ?-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.
Packaging
1, 5 g in poly bottle
| Quality Level | 200 |
|---|---|
| Pack | 1G |
| mp | >278 °C (dec.) (lit.) |
| InChI key | HFHDHCJBZVLPGP-RWMJIURBSA-N |
| InChI | 1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5- |
| Manufacturer | SIGMA-ALDRICH |
| Product Line | BioReagent |
| Form | powder |
| Assay | ≥98% |
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