alpha-Cyclodextrin, powder, BioReagent, suitable for cell culture, >=98%

alpha-Cyclodextrin, powder, BioReagent, suitable for cell culture, >=98%

Stock Code: 3571448
Manufacturer Part No: C4680-1G
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£89.13 (exc VAT) per 1G
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Application


Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. ?-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.


Biochem/physiol Actions


?-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, ?-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, ?-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.


General description


?-Cyclodextrin (?-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by ?-(1,4) bonds. ?-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.


Packaging


1, 5 g in poly bottle

Quality Level200
Pack1G
mp>278 °C (dec.) (lit.)
InChI keyHFHDHCJBZVLPGP-RWMJIURBSA-N
InChI1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-
ManufacturerSIGMA-ALDRICH
Product LineBioReagent
Formpowder
Assay≥98%

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