3,3-Dithiodipropionic acid di(N-hydroxysuccinimide ester), powder
Application
3,3?-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.
Caution
Avoid use of reducing agents during coupling reactions.
Features and Benefits
The disulfide linkage is cleavable by mild reduction.
General description
3,3?-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
| Quality Level | 200 |
|---|---|
| InChI key | FXYPGCIGRDZWNR-UHFFFAOYSA-N |
| InChI | 1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Solubility | chloroform: 50 mg/mL, acetone: soluble, DMF: soluble |
| Form | powder |
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