3-Maleimidobenzoic acid N-hydroxysuccinimide ester, crystalline

Stock Code: 3587144
Manufacturer Part No: M2786-25MG

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Descriptions

Application

3-Maleimidobenzoic acid N-hydroxysuccinimide ester (MBS) has been used as a protein cross-linker. It has been used for the stabilization of actin filaments in plant tissue samples.

3-Maleimidobenzoic acid N-hydroxysuccinimide ester has been used:in the fixation of pollen in Arabidopisas a component of Murashige and Skoog (MS) medium to stabilize F-actin in Eucalyptus root hairsin the fixation of F-actin labelled pollen tubes of Lilium davidii

Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.0, followed by coupling to compounds containing sulfhydryl by thioether at same pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Biochem/physiol Actions

3-Maleimidobenzoic acid N-hydroxysuccinimide is used as a fixative for the preservation of pollen tube F-actin distribution. It imposes less damage when used on pollen tubes.

Other Notes

The aryl maleimide is less stable than alkyl maleimide linkers.

Packaging

100 mg in glass bottle

25 mg in poly bottle

Specifications

Quality Level	200
mp	175-177 °C (lit.)
InChI key	LLXVXPPXELIDGQ-UHFFFAOYSA-N
InChI	1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: ≤20 mg/mL (may require addition of solvent to coupling buffer to at least 5% to maintain solubility)
Form	crystalline