(-)-Riboflavin, BioReagent, suitable for cell culture, suitable for insect cell culture, >=98%

(-)-Riboflavin, BioReagent, suitable for cell culture, suitable for insect cell culture, >=98%

Stock Code: 3572230
Manufacturer Part No: R9504-25G
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£66.88 (exc VAT) per 25G
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Application


(-)-Riboflavin has been used to administer intraperitoneally to experimental mice to study its protective role in stroke in middle cerebral artery occlusion. It has also been used with Krebs? solution, to model ischemia-like conditions in vitro.


Biochem/physiol Actions


Riboflavin serves as a precursor for the active enzyme cofactors riboflavin 5?-monophosphate (also called flavin mononucleotide or FMN) and flavin adenine dinucleotide (FAD). Riboflavin deficiency in the diet results in a well-defined syndrome known as ariboflavinosis, having symptoms including cheilosis, angular stomatitis, glossitis, keratitis, and seborrhoeic dermatitis. Riboflavin exhibits protective effects against tumor development and cardiovascular disease. Its deficiency often affects metabolism involving redox reactions. Riboflavin is found essential for iron absorption, gastrointestinal development, neurogenesis, corneal vascularization and corneal opacity.


General description


Riboflavin is an essential vitamin soluble in water. Milk and eggs are found to be its major sources. Riboflavin is usually bound to enzymes in all tissues. During riboflavin localization in plasma, it is bound to albumin and specific immunoglobulins.


Packaging


25, 100 g in glass bottle

Colouryellow to orange
Pack25G
mp290 °C (dec.) (lit.)
InChI keyAUNGANRZJHBGPY-SCRDCRAPSA-N
InChI1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98%

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