(2-Hydroxypropyl)-gamma-cyclodextrin, solid
Application
Useful for solubilization of macromolecule, such as cholesterol, used in cell culture applications. Similar to β cyclodextrin, but able to solubilize larger molecules.
Biochem/physiol Actions
Harmalol, a harmala (β-carboline) alkaloid, is a monoamine oxidase inhibitor (MAOi) useful for studies involving melanogenesis. Harmalol is use in β-carboline nucleic acid (DNA and RNA) binding studies.
Other Notes
Non-toxic solubilizer. γ-Cyclodextrin (8-glucose units) has a slightly larger cavity and can accommodate larger substrates than β-cyclodextrin.
Packaging
1 g in glass bottle
| Colour | white |
|---|---|
| Quality Level | 100; 100 |
| Pack | 5G |
| mp | 264-267 °C (dec.) (lit.) |
| InChI key | OYKGNQNESCZSHQ-UHFFFAOYSA-N |
| InChI | 1S/C12H12N2O.ClH.2H2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12;;;/h2-3,6,14-15H,4-5H2,1H3;1H;2*1H2 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: 450 mg/mL |
| Form | solid |
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