(+)-Sodium L-ascorbate, powder, BioReagent, suitable for cell culture
Application
(+)-Sodium L-ascorbate has been used:to produce H2O2 in cell culture mediaas a reducing agent for a cell-permeable artificial electron donor, N,N,N?,N?-tetramethyl-p-phenylenediamine (TMPD)to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat
Used for preparation of plant extracts; reductant for the isolation of chloroplasts.
Biochem/physiol Actions
Antioxidant
General description
(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid). It is widely used as a food additive. In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture. Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats. sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.
Packaging
1 kg in poly bottle
100, 500 g in poly bottle
| Colour | white to off-white |
|---|---|
| Pack | 1KG |
| mp | 220 °C (dec.) (lit.) |
| InChI key | PPASLZSBLFJQEF-RXSVEWSESA-M |
| InChI | 1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1 |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
| Assay | ≥98% |
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