Phe-Arg beta-naphthylamide dihydrochloride, cathepsin substrate

Phe-Arg beta-naphthylamide dihydrochloride, cathepsin substrate

Stock Code: 3578664
Manufacturer Part No: P4157-250MG
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£948.54 (exc VAT) per 250MG
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Application


Phe-Arg -naphthylamide dihydrochloride has been used to evaluate the contribution of efflux pumps to antimicrobial resistance. It has also been used for minimal inhibitory concentration testing in the presence of an efflux pump inhibitor.


General description


Phe-Arg ?-naphthylamide, a peptidomimetic compound, is an efflux pump inhibitor (EPI). It acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. Phe-Arg -naphthylamide lowers fluoroquinolone resistance in Pseudomonas aeruginosa.


Packaging


Bottomless glass bottle. Contents are inside inserted fused cone.


Substrates


Substrate for dipeptidyl aminopeptidase I (cathepsin C).

Quality Level200
InChI keyZMTAZQYLEGNUTJ-UHFFFAOYSA-N
InChI1S/C25H30N6O2.ClH/c26-21(15-17-7-2-1-3-8-17)23(32)31-22(11-6-14-29-25(27)28)24(33)30-20-13-12-18-9-4-5-10-19(18)16-20;/h1-5,7-10,12-13,16,21-22H,6,11,14-15,26H
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Solubilitywater: 50 mg/mL, clear, colorless to faintly yellow
Formpowder
Assay≥98% (TLC)

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