Oxaloacetic acid, >=97%

Oxaloacetic acid, >=97%

Stock Code: 3578641
Manufacturer Part No: O4126-100G
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Application


Oxaloacetic acid has been used as a substrate for measuring citrate synthase activity in cybrids and neuroblastoma cells. It has also been used for measuring malate dehydrogenase reactivation.


Biochem/physiol Actions


Oxaloacetic acid being an intermediate in the tri carboxylic cycle is central to metabolism. It is part of gluconeogenesis pathway. Mutation in pyruvate carboxylase leads to decreased production of oxaloacetate. It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism.


General description


Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid.


Packaging


1, 5, 25, 100 g in poly bottle

Quality Level200
InChI keyKHPXUQMNIQBQEV-UHFFFAOYSA-N
InChI1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityH2O: 100 mg/mL, clear to slightly hazy, colorless to light yellow
Formpowder
Assay≥97% (HPLC)

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