Nalpha-Benzoyl-DL-arginine beta-naphthylamide hydrochloride, trypsin substrate

Nalpha-Benzoyl-DL-arginine beta-naphthylamide hydrochloride, trypsin substrate

Stock Code: 3578165
Manufacturer Part No: B4750-1G
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Application


N?-Benzoyl-DL-arginine ?-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.


Biochem/physiol Actions


N?-Benzoyl-DL-arginine ?-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.


Substrates


A chromogenic substrate for trypsin.

Quality Level200
InChI keyBNGRKDJZQIGWQF-UHFFFAOYSA-N
InChI1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,2
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMF: 50 mg/mL, clear, colorless to faintly yellow
Formpowder
Assay≥98% (TLC)

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