Methylglyoxal solution, approx. 40% in H2O

Methylglyoxal solution, approx. 40% in H2O

Stock Code: 3578407
Manufacturer Part No: M0252-500ML
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Application


Methylglyoxal solution has been used:to assess glyoxalase 1 (GLO1) enzymatic activityas an advanced glycation end (AGE) forming agent for the preparation of albumin in vitroto regulate anxiety like behavior in miceto induce peritoneal fibrosis in ratsto study the chromatographic retention characteristics of organic chemicals and metal DNA adductsfor intraplantar injection in mice to investigate peripheral and central components of methylglyoxal (MG)-transient receptor potential ankyrin 1 (TRPA1)-adenylyl cyclase 1 isoform (AC1) pathway


General description


Methylglyoxal (MG) is a glucose metabolite, which is linked to peripheral neuropathy and pain in diabetic patients. It enhances intracellular calcium in sensory neurons and produces behavioral nociception. Methylglyoxal has antibacterial property. MG functions as a protein-glycating agent and precursor of advanced glycation end products. It impairs diabetic wound healing.

Quality Level200
InChI keyAIJULSRZWUXGPQ-UHFFFAOYSA-N
InChI1S/C3H4O2/c1-3(5)2-4/h2H,1H3
ManufacturerSIGMA-ALDRICH
Density1.17 g/mL at 25 °C (lit.)
Formliquid
Assay~40% (enzymatic)

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