Idebenone, >=98% (HPLC)

Idebenone, >=98% (HPLC)

Stock Code: 3578347
Manufacturer Part No: I5659-100MG
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£791.14 (exc VAT) per 100MG
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Application


Idebenone has been used:to treat mutant myocilin (mMYOC) cellsfor drug treatment assayto validate C2C12 secondary cell screening assayto treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPAR?, ? and ? LBDs


Biochem/physiol Actions


A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.


Idebenoneis used in the treatment of visual impairment in adolescents and adults with Leber?s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.


General description


Idebenone is a short-chain benzoquinone drug.


Packaging


100 mg in poly bottle


25 mg in glass insert

Quality Level200
InChI keyJGPMMRGNQUBGND-UHFFFAOYSA-N
InChI1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
Solubilitymethanol: 50 mg/mL, clear to slightly hazy
Formpowder
Assay≥98% (HPLC)

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