DL-beta-Hydroxybutyric acid sodium salt, approx.98%
Application
DL-?-Hydroxybutyric acid sodium salt has been used:as a standard for quantifying blood plasma and milk ?-hydroxybutyric acid in Danish Jersey cowsto investigate its anticonvulsant effects in epilepsy induced ratsto induce hyperketonemia in Holstein dairy cows
Biochem/physiol Actions
?-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of ?-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. ?-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson?s disease model. ?-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).
Packaging
5, 25, 100 g in poly bottle
| Quality Level | 200 |
|---|---|
| InChI key | NBPUSGBJDWCHKC-UHFFFAOYSA-M |
| InChI | 1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | water: 1 g/10 mL, clear, colorless |
| Form | powder |
| Assay | ~98% |
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