beta-Chloro-L-alanine hydrochloride, Alanine aminotransferase inhibitor
Application
?-Chloro-L-alanine hydrochloride has been used:as a substrate for screening tyrosine phenol lyase steady state kineticsin the inhibition of serine palmitoyltransferase and cytotoxicity studies in lymphocyte Ly-1 cellsas an inhibitor of alanine transaminase in wheat germ cell-free protein synthesis system
Biochem/physiol Actions
?-Chloro-L-alanine hydrochloride is an inhibitor of alanine aminotransferase (ALAT). Inhibition of ALAT leads to suppression of tumor progression in lung carcinoma.
| Quality Level | 200 |
|---|---|
| mp | 205 °C |
| InChI key | IENJPSDBNBGIEL-DKWTVANSSA-N |
| InChI | 1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m0./s1 |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
| Assay | ≥98% (TLC) |
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