Cortistatin-14, >=97% (HPLC)

Cortistatin-14, >=97% (HPLC)

Stock Code: 3577679
Manufacturer Part No: C5808-1VL
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Application


Cortistatin-14 may be used in competition binding assay with sst4 receptors (CHO-sst4) of CHO cells and sst1 receptors (CHO-sst1).


Biochem/physiol Actions


Cortistatin-14, like somatostatin inhibits the physiological activity of hippocampal neurons. It binds and exerts its function through all the somatostatin receptors (sst1-sst5). It shows anticonvulsive and neuroprotective effect. Cortistatin-14 has remarkable anti-inflammatory properties.


Somatostatin-like neuropeptide with neuronal depressant and sleep modulating properties. Exogenous cortistatin impairs short-term memory processing.


General description


Cortistatin-14 is a neuropeptide have structural similarity to somatostatin-14. It is produced in the cortex and hippocampus of central nervous system. In the peripheral system, it is produced in adrenal, thyroid, parathyroid, stomach, intestine, pancreas, testes, liver and kidney.

Quality Level200
InChI keyDDRPLNQJNRBRNY-WYYADCIBSA-N
InChI1S/C81H113N19O19S2/c1-46(103)67-80(117)95-59(38-49-24-9-4-10-25-49)73(110)96-62(42-101)76(113)97-63(43-102)77(114)99-65(79(116)90-56(81(118)119)30-15-18-34-84)
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥97% (HPLC)

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