Lycorine hydrochloride, >=98% (TLC), powder
Biochem/physiol Actions
A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.
Caution
Protect from light.
| Quality Level | 100 |
|---|---|
| mp | 210-212 °C |
| InChI key | VUVNTYCHKZBOMV-NVJKKXITSA-N |
| InChI | 1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | ethanol: 10 mg/mL, clear, colorless to very faintly yellow |
| Form | powder |
| Assay | ≥98% (TLC) |
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