NSC23925, >=98% (HPLC)

Stock Code: 3574051
Manufacturer Part No: SML0372-25MG

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Descriptions

Biochem/physiol Actions

NSC23925 is a specific Pgp1 inhibitor. It reverses MDR1 (Pgp1) but does not inhibit MRP or BCRP-mediated MDR. NSC23925 itself is not a substrate of Pgp1 but stimulates ATPase activity of Pgp, directly inhibiting the function of Pgp1 in a dose-dependent manner without altering the total expression level of Pgp1.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	white to beige
Quality Level	100
InChI key	WGWOQHWZXLGPNG-UHFFFAOYSA-N
InChI	1S/C22H24N2O2.2ClH/c1-26-16-11-9-15(10-12-16)21-14-18(17-6-2-3-7-19(17)24-21)22(25)20-8-4-5-13-23-20;;/h2-3,6-7,9-12,14,20,22-23,25H,4-5,8,13H2,1H3;2*1H
Manufacturer	SIGMA-ALDRICH
Solubility	H2O: 5 mg/mL (clear solution)
Form	powder
Assay	≥98% (HPLC)