Chromeceptin, >=98% (HPLC), solid

Stock Code: 3573297
Manufacturer Part No: C0868-5MG
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Biochem/physiol Actions


Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.


Features and Benefits


This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colouryellow to brown
Quality Level100
InChI keyGVINXTXGDDSXFQ-UHFFFAOYSA-N
InChI1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3
ManufacturerSIGMA-ALDRICH
SolubilityH2O: ﹤2 mg/mL, DMSO: >20 mg/mL
Formsolid
Assay≥98% (HPLC)

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