Umbelliferyl Arachidonate, ethanol solution

Umbelliferyl Arachidonate, ethanol solution

Stock Code: 3593813
Manufacturer Part No: U0383-10MG
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£213.76 (exc VAT) per 10MG
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Application

Umbelliferyl Arachidonate also known as 7-Hydroxycoumarinyl Arachidonate was used as a fluorogenic substrate for developing a fluorescence-based assay to evaluate the inhibitors against human recombinant monoacylglycerol lipase.

Biochem/physiol Actions

Monoacylglycerol lipase (MAGL) protein facilitates the hydrolysis of Umbelliferyl Arachidonate and generates arachidonic acid and the highly fluorescent 7-hydroxyl coumarin (7-HC). Hence, it acts as a marker in a fluorescence-based assay.

Preparation Note

Umbelliferyl Arachidonate can be dissolved in DMSO at 25 mg/ml and in DMF at 50 mg/ml. The product is sparingly soluble in aqueous buffers.

Quality Level200
InChI keySFTGFGOBCQCZDY-DOFZRALJSA-N
InChI1S/C29H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(30)32-26-22-20-25-21-23-29(31)33-27(25)24-26/h6-7,9-10,12-13,15-16,20-24H,2-5,8,11,14,17-19H2,1
ManufacturerSIGMA-ALDRICH
Formethanol solution
Assay≥98% (HPLC)

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