SMAD5, GST tagged human, recombinant, expressed in E. coli, >=70% (SDS-PAGE), buffered aqueous glyce

SMAD5, GST tagged human, recombinant, expressed in E. coli, >=70% (SDS-PAGE), buffered aqueous glyce

Stock Code: 3593391
Manufacturer Part No: SRP5134-50UG
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

General description

SMAD5 is a member of the SMAD family and mediates signaling by the transforming growth factor-beta (TGFβ) superfamily and related ligands. SMAD5 plays a critical role in the signaling pathway by which TGFβ inhibits the proliferation of human hematopoietic progenitor cells. SMAD5 is up-regulated in gastric epithelial cells during the infection of the pathogen Helicobacter pylori and it mediates apoptosis of gastric epithelial cells induced by H. pylori infection. In mature human B cells, bone morphogenetic protein 6 (BMP-6) inhibits cell growth and rapidly induces phosphorylation of SMADs 5 and 8.

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

ManufacturerSIGMA-ALDRICH
Storage Temp.−70°C
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

There are no downloads for this product.