Prostate Specific Antigen Substrate, >=97% (HPLC)

Prostate Specific Antigen Substrate, >=97% (HPLC)

Stock Code: 3592502
Manufacturer Part No: SCP0224-1MG
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Amino Acid Sequence

Mu-His-Ser-Ser-Lys-Leu-Gln-AMC

Application

Prostate Specific Antigen Substrate has been used to assay recombinant severe acute respiratory syndrome coronavirus-2 viral 3-chymotrypsin-like cysteine protease (SARS-CoV-2 3CLpro).

Biochem/physiol Actions

Prostate specific antigen (PSA). It exhibits chymotrypsin-like activity. PSA is the most abundant proteasefound in the prostate and secreted into the seminal fluid. It is a useful biomarker for prostate cancer. PSA digests the gel-forming proteins semenogelins I and II in semen. It shows antiangiogenic activityin vitroandin vivo.

General description

Prostate specific antigen (PSA) is a kallikrein-related serine peptidase that belongs to the chymotrypsin subfamily serine protease. It was originally found in human semen. PSA is also detected in serum correlated to benign and metastatic disease.

ManufacturerSIGMA-ALDRICH
CompositionPeptide Content, ≥75%
Storage Temp.−20°C
Formlyophilized
Assay≥95% (HPLC)

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