Albumin from human serum, lyophilized powder, low endotoxin

Albumin from human serum, lyophilized powder, low endotoxin

Stock Code: 3589574
Manufacturer Part No: A5843-5G
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Application

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.

Biochem/physiol Actions

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

General description

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Other Notes

View more information on human serum albumin.

Quality Level200
ManufacturerSIGMA-ALDRICH
Impurities≤1.0 EU/mg endotoxin, HIV I and HIVII, HCV and HBsAg, tested negative
SolubilityH2O: soluble 50 mg/mL
Formlyophilized powder
Assay≥96% (agarose gel electrophoresis)

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