AMPK (alpha1/beta2/gamma1), active, His tagged human, PRECISIO Kinase, recombinant, expressed in bac

Stock Code: 3589537
Manufacturer Part No: A4611-10UG

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Descriptions

Biochem/physiol Actions

AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an A catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and 3-hydroxy-3-methylglutaryl-CoA reductase. The β subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol.