N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide, >=97% (HPLC), powder

Stock Code: 3589480
Manufacturer Part No: A2559-5MG
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Amino Acid Sequence

NAc-Asp-Glu-Val-Asp-pNA

Application

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

Biochem/physiol Actions

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

Packaging

5 mg in glass bottle

Colourwhite
Quality Level100
InChI keyGGXRLUDNGFFUKI-ORGXJRBJSA-N
InChI1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥97% (HPLC)

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