AMPK (alpha1/beta1/gamma1), active, His tagged human, PRECISIO Kinase, recombinant, expressed in bac

Stock Code: 3589409
Manufacturer Part No: A1233-10UG

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Descriptions

Biochem/physiol Actions

AMPK is a heterotrimer protein kinase consisting of a A catalytic subunit, and non-catalytic β and γ subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.