Dexamethasone, Ph Eur

Dexamethasone, Ph Eur

Stock Code: 3589271
Manufacturer Part No: 31375-500MG
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£232.57 (exc VAT) per 500MG
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Application

Dexamethasone has been used as a DMEM medium supplement utilized in osteogenesis. It has also been used as an alpha-MEM medium supplement to initiate adipogenic differentiation. Additionally, it has also been used to study apoptosis, cell signaling pathways and gene expression.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Dexamethasone is a glucocorticoid anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. Additionally, dexamethasone inhibits the induction of nitric oxide synthase. It induces apoptosis by initiating the initial cleavage of DNA into high molecular weight fragments.

mp262-264 °C (lit.)
InChI keyUREBDLICKHMUKA-CXSFZGCWSA-N
InChI1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+
ManufacturerSIGMA-ALDRICH
Agencytested according to Ph. Eur., USP/NF
Formsolid
Assay99.60%

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