ROCHE Insulin humanrecombinant (yeast)

ROCHE Insulin humanrecombinant (yeast)

Stock Code: 2795589
Manufacturer Part No: 11376497001
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Application


Insulin shows a broad range of activities on a variety of somatic cells. Recombinant human insulin can be used to stimulate growth and proliferation of cultured cells and to investigate insulin activity on sensitive cells used in research studies. It is also a component of serum-free media formulations for most primary cells and cell lines.


Biochem/physiol Actions


Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.


General description


Recombinant Insulin, human, is produced in yeast and purified by standard chromatographic techniques. Insulin regulates blood glucose. In muscles and adipocytes it stimulates glucose intake and metabolism. It also controls the expression and various enzymes.


Other Notes


For life science research only. Not for use in diagnostic procedures.


InChI:

InChI keyPBGKTOXHQIOBKM-FHFVDXKLSA-N
Impurities﹤0.1 EU/µg endotoxin (LAL test)
Formlyophilized (clear, colorless solution after reconstitution)
Assay>98% (SDS-PAGE)

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