ROCHE Plasmin humanfrom human plasma

Stock Code: 2795430
Manufacturer Part No: 10602361001

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Descriptions

Application

Human plasmin has been used as an oligopeptide substrate in peptidase inhibition assays.

Biochem/physiol Actions

Plasmin is a direct acting fibrinolytic enzyme present in blood. Its activity is independent of plasminogen presence during fibrinolysis. Plasmin is rapidly and irreversibly inhibited by ?-2 antiplasmin.

General description

Inhibitors: DFP, PMSF, TLCK, leupeptin, aprotinin, soybean trypsin inhibitor, α₁-antitrypsin, α₂-macroglobulin, anti-thrombin III heparin, APMSF, and α₂-antiplasmin

Fibrinolysin

Other Notes

For life science research only. Not for use in diagnostic procedures.

Physical form

Suspension in 3.2 M ammonium sulfate solution

Preparation Note

Stabilizers: Human plasmin does not contain stabilizers.Storage conditions (working solution): 2 to 8 °CDiluted solution (pH 8.6) is stable at 2 to 8 °C for at least 1–2 weeks. For storage of dialyzed solution freezing in aliquots is recommended.

Specificity

Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.

Storage and Stability

Store at 2 to 8 °C. (Recommended form for storage is ammonium sulfate suspension 3.2 M, pH 8.6.)