ROCHE Glucose-6-phosphate

Stock Code: 2795387
Manufacturer Part No: 10127647001
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Application


Substrate for glucose-6-phosphatase.


Biochem/physiol Actions


In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.


Components


77% glucose-6-P (enzymatic), 13% sodium, 8% water


Formula variant


C6H11O9PNa2


General description


Disodium salt


Other Notes


For life science research only. Not for use in diagnostic procedures.


Quality


Contaminants: ﹤0.2% glucose (enzymatic)

InChI keyUUWJZXLTPORJKW-WYFATIGWSA-L
InChI1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
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