Zardaverine, phosphodiesterase inhibitor

Stock Code: 2794309
Manufacturer Part No: Z3003-5MG

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Descriptions

Application

Zardaverine has been used as a phosphodiesterase inhibitor:to study its effects on human colonic epithelial cellsto study its effects on junctional proteins in Sertoli cellsto study its effects on phosphodiesterase3A (PDE3A) expression in various tumor cells

Biochem/physiol Actions

Zardaverine is a derivative of pyridazinone. It shows anti-tumor and anti-proliferative activity in varied cell lines. Zardaverine possesses broncho-dilatory activity and exhibits therapeutic effects against asthma.

Selective inhibitor of phosphodiesterase III/IV (PDE3/4).

Specifications

Quality Level	200
InChI key	HJMQDJPMQIHLPB-UHFFFAOYSA-N
InChI	1S/C12H10F2N2O3/c1-18-10-6-7(2-4-9(10)19-12(13)14)8-3-5-11(17)16-15-8/h2-6,12H,1H3,(H,16,17)
Form	powder
Assay	≥98% (HPLC)