KININOGENHMWHUMAN PLASMA

Stock Code: 3576951
Manufacturer Part No: SRP6318-100UG

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Descriptions

General description

HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.

Physical form

Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI.