BML-259

Stock Code: 3576909
Manufacturer Part No: SRP0704-25MG

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Descriptions

Biochem/physiol Actions

Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM) ⁽¹⁾. Protects cells against NAC-amyloid-induced cell death ⁽²⁾. Cell permeable. MW=260.4. Purity ?95% by TLC. Formulated as a lyophilized powder. May be dissolved in DMSO (>25 mg/mL) or DMF (30 mg/mL). Stable desicated as supplied at ambient temperature for up to 2 years, or in solution at -20°C for up to 2 months.

Storage and Stability

Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 2 months.